Glycol
Glycol
Glycol or Dihydric
alcohols are compounds containing two hydroxyl groups. They are classified as α, β, γ… glycols, according to the relative positions of the two hydroxyl groups: α is the 1,2 glycol; β, 1,3; my. 1,4,…. Although it is unusual to find a
compound with two hydroxyl groups attached to the same carbon atom, ether
derivatives of these 1, 1 glycols are stable, e.g., acetals. The commonest
glycols are the α-glycols.
Nemenclatrue
The common
names of the α-glycols are derived from the corresponding alkene from which
they may be prepared by direct hydroxylation, e.g.
HOCH2CH2OH eethylene
glycol
(CH3)2COHCH2OH isobutene glycol
β-, γ-…
Glycols are named as the corresponding polymethylene glycols, e.g.,
HOCH2CH2OH trimethylene glycol
HOCH2CH2CH2CH2CH2OH pentamethylene
glycol
According to
the I.U.P.A.C. system of nomenclature, the class suffix is –diol, and numbers
are used to indicate the positions of side-chains and the two hydroxyl groups,
e.g.,
Preparation of Glycol
Ethylene
glycol, glycon (ethane-1,2-diol), is the
simplest glycol, and may be prepared as follows:
1. By passing
ethylene into cold dilute alkaline permanganate solution.
2. By passing
ethylene into hypochlorous acid and then hydrolyzing the ethylene chlorohydrins
by boiling with aqueous sodium hydrogen carbonate:
CH=CH2 + HOCl ⟶ CICH2CH2OH (aq. NaHCO3) ⟶ HOCH2CH2OH + NaCl + CO2
3. By boiling
ethylene dibromide with aqueous sodium carbonate:
BrCH2CH2Br +
NaCO3 + H2O ⟶ HOCH2CH2OH
+ 2NaBr + CO2 (50%)
The low
yield in this reaction is due to conversion of some ethylene dibromide into
vinyl bromide:
BrCH2CH2Br + Na2CO3 ⟶ CH2=CHBr + NaBr
+ NaHCO3
If aqueous
sodium hyrooxide is used instead of sodium carbonate, vinyl bromide is again
obtained as a by-product. The best yield of glycol is obtained by heating
ethylene dibromide with potassium acetate in glacial acetic acid, and
subsequently hyroolysing the glycol diacetate with hydrogen chloride in methanolic
solution
BrCH2CH2Br +
2CH3CO2K ⟶ CH2(OCOCH3)CH2(PCPCH3) +
2KBr (HCl) ⟶ HOCH2CH2OH
(90%) (83-84%)
4. By treating
ethylene oxide with dilute hydrochloric acid :
Glycol is
prepared industrially by method (4), and by the catalytic reduction of methyl
glycollate which is produced synthetically.
Glycol is a colorless
viscous liquid, b.p.197oC, and has a sweet taste (the prefix glyc-
indicates that the compound has a sweet taste) it is miscible in all proportion
with water and ethanol, but is insoluble in ether. It is widely used as a
solvent and as an antifreeze agent.
The high
boiling points and high solubility in water of polyhydric alcohols are due to
hydrogen bonding involving all hydroxyl groups.
The chemical
reactions of glycol are those which might have been expected of a monohydric
primary alcohol. One hydroxyl group, however, is almost always completely
attacked before the other reacts.
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